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Electrospinning has attracted great interest for making tissue engineering scaffolds Given that bone morphogenetic protein-2 (BMP-2) can induce osteogenic differentiation of mesenchymal stem cells (MSCs) and synthetic calcium phosphates (Ca-P) are osteoconductive electrospun scaffolds incorporating both BMP-2 and Ca-P could have a synergistic effect on bone formation
Electrospun nanofibrous structure: A novel scaffold for tissue engineering Wan-Ju Li 1 4* Cato T Laurencin 2 Edward J Caterson 4 Rocky S Tuan 4 * Frank K Ko1 3 1School of Biomedical Engineering Science and Health Systems Drexel University Philadelphia Pennsylvania 19104 2Department of Chemical Engineering Drexel University Philadelphia Pennsylvania 19104
Electrospinning is a technique for creating continuous nanofibrous networks that can architecturally be similar to the structure of extracellular matrix (ECM) However the shrinkage of electrospun mats is unfavorable for the triggering of cell adhesion and further growth In this work electrospun PLGA nanofiber assemblies are utilized to create a scaffold
Skin burn wounds are a crucial issue that could reduce life quality Although numerous effective skin products have invaded the biomedical market most of them still demonstrate some limitations regarding their porosity swelling and degradation behaviors antibacterial properties and cytotoxicity Thus the aim of this study is to fabricate novel trilayered asymmetric porous scaffolds that
The results showed that the fabricated PCL/AV/CUR and PCL/AV/TCH nanofibrous scaffolds were non-toxic and had the potential for wound healing applications The disc diffusion assay confirmed that the electrospun nanofibrous scaffolds possessed antibacterial activity and provided an effective wound dressing for skin tissue engineering
Nanofibrous scaffolds can be associated with another advanced technique in recent tissue engineering—controlled delivery of various types of stem cells such as bone marrow mesenchymal stem cells [51 61–63] adipose tissue-derived stem cells [64 65] neural tissue
Oct 10 2019Antonios Keirouz Michael Chung Jaehoon Kwon Giuseppino Fortunato Norbert Radacsi 2D and 3D electrospinning technologies for the fabrication of nanofibrous scaffolds for skin tissue engineering: A review WIREs Nanomedicine and
Oct 18 2008The last decade has seen significant progress in the production of nanofibers by electrospinning One of the major drivers to this progress is the potential use of nanofibrous structures as scaffolds for engineering tissues in regenerative medicine Electrospun fibers are capable of emulating the nanofibrous architecture of the native extracellular matrix
The results showed that the fabricated PCL/AV/CUR and PCL/AV/TCH nanofibrous scaffolds were non-toxic and had the potential for wound healing applications The disc diffusion assay confirmed that the electrospun nanofibrous scaffolds possessed antibacterial activity and provided an effective wound dressing for skin tissue engineering
Exploring Nanofibrous Self-assembling Peptide Hydrogels Using Mouse Myoblast Cells for 3D Bioprinting and Tissue Engineering Applications "Submmited" 4 Wafaa T Arab Hepi H Susapto Dana M Al-Hattab and Charlotte AE Hauser (2019) Peptide nanogels as scaffold for fabricating dermal grafts and 3D skin models "under preparation" 5
NANOFIBROUS SCAFFOLD FOR SKIN TISSUE ENGINEERING JIN GUORUI (Bachelor of Engineering Harbin Institute of Technology China) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF MECHANICAL ENGINEERING NATIONAL UNIVERSITY OF SINGAPORE 2013
Aloe vera (AV) and tetracycline hydrochloride (TCH) exhibit significant properties such as anti-inflammatory antioxidant and anti-bacterial activities to facilitate skin tissue engineering The present study aims to develop poly-ε-caprolactone (PCL)/ AV containing curcumin (CUR) and TCH loaded hybrid nanofibrous scaffolds
Journal of biomedical nanotechnology 2014-4-23 Bi-layer scaffold of chitosan/PCL-nanofibrous mat and PLLA-microporous disc for skin tissue engineering [Tao Lou Matthew Leung Xuejun Wang Julia Yu Fong Chang Ching Ting Tsao Jonathan Ghing Chi Sham Dennis Edmondson Miqin Zhang]
Electrospinning is a technique for creating continuous nanofibrous networks that can architecturally be similar to the structure of extracellular matrix (ECM) However the shrinkage of electrospun mats is unfavorable for the triggering of cell adhesion and further growth In this work electrospun PLGA nanofiber assemblies are utilized to create a scaffold
NANOFIBROUS SCAFFOLD FOR SKIN TISSUE ENGINEERING JIN GUORUI (Bachelor of Engineering Harbin Institute of Technology China) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF MECHANICAL ENGINEERING NATIONAL UNIVERSITY OF SINGAPORE 2013
Imparting bioactivity in addition to the structural features of the scaffold has enabled the creation of multiple tissue engineering scaffolds with tissue-specific functions 4 Electrospun nanofibers for skin tissue regeneration Skin is the largest organ of the body and provides an external barrier to protect against pathogen invasion As
Smaranda Badea Wutian Wu in Nanoengineered Biomaterials for Regenerative Medicine 2019 4 3 Electrospun Nanofibrous Scaffolds Nanofibrous scaffolds can be generated by a variety of techniques of which electrospinning has been used extensively for tissue engineering purposes [117] The recent development of novel nanofibrous scaffolds has correlated with the increased
multifunctional nanofibrous scaffolds appropriate for engineering hierarchical tissue construct using electrospun nanofibres Polycaprolactone (PCL) a biodegradable and biocompatible synthetic polymer [26 27] was used as the base material to explore all the possibilities Bioactive nanofibres containing either collagen type I bovine
for bone tissue engineering J Venugopal P Vadgama T S Sampath Kumar et al -Fabrication of a nanofibrous scaffold with improved bioactivity for culture of human dermal fibroblasts for skin regeneration Arun Richard Chandrasekaran J Venugopal S Sundarrajan et al -Surface modified electrospun nanofibrous scaffolds for nerve tissue engineering
Nanofibrous Scaffolds for Tissue Engineering Applications Braz Arch Biol Technol v 59: e16150644 Jan/Dec 2016 3 scaffold was vapour crosslinked with 0 5% (v/v) glutaraldehyde dissolved in ethanol Crosslinked scaffold were washed thoroughly with deionized water to
Electrospun nanofibrous scaffolds have been widely used in cardiac tissue engineering because they can mimic the extracellular matrix of myocardium Developing conductive nanofibrous scaffolds by electrospinning would be beneficial for cardiomyocytes-based bioactuators but such scaffolds have been rarely reported
In this review paper the definition of the tissue engineering (TE) was comprehensively explored towards scaffold fabrication techniques and applications Scaffold properties and features in TE biological aspects scaffold material composition scaffold structural requirements and old and current manufacturing technologies were reported and discussed In almost all the reviewed reports the
Polysaccharide nanofibrous scaffolds as a model for in vitro skin tissue regeneration: a natural polysaccharide was electrospun along with polyvinyl alcohol (PVA) to produce Xylan/PVA nanofibers for skin tissue engineering The Xylan/PVA glutaraldehyde (Glu) vapor cross-linked nanofibers were characterized by SEM FT-IR tensile testing and
preparation and characterization of scaffolds of collagen/ PEO nanofibers incorporated with gold nanoparticles for skin tissue engineering applications It is proposed in the current study that the advantageous properties of collagen nanofibrous matrix such as similar nanofibrous structure to skin and the proven wound healing effect reported
Xin Jing Heng Li Hao-Yang Mi Yue-Jun Liu Yi-Min Tan Fabrication of Three-Dimensional Fluffy Nanofibrous Scaffolds for Tissue Engineering via Electrospinning and CO 2 Escaping Foaming Industrial Engineering Chemistry Research 10 1021/acs iecr 9b00935 (2019)
Electrospun nanofibrous structure: A novel scaffold for tissue engineering Wan-Ju Li 1 4* Cato T Laurencin 2 Edward J Caterson 4 Rocky S Tuan 4 * Frank K Ko1 3 1School of Biomedical Engineering Science and Health Systems Drexel University Philadelphia Pennsylvania 19104 2Department of Chemical Engineering Drexel University Philadelphia Pennsylvania 19104
The proliferation of fibroblast on the PHBV/SF nanofibrous scaffold with 50/50 was higher than that on the pure PHBV nanofibrous scaffold Our results indicated that the PHBV/SF nanofibrous scaffold with 50/50 may be a better candidate for biomedical applications such as skin tissue engineering and wound dressing POLYM ENG
Tissue engineering and drug delivery are closely related areas in biomedical field and the release of the therapeutic factors may enhance the efficacy of tissue engineering scaffolds Goldberg et al reported various nano-structured materials for drug delivery combined with tissue engineering applications [ 83 ]
These results show that the PCL/Ge (70 : 30) nanofibrous scaffold was more favourable and has the potential to be a promising scaffold for skin tissue engineering applications The fabrication of biocompatible and biodegradable scaffolds which mimic the native extracellular matrix of tissues to promote cell adhesion and growth is emphasized
Nanofibrous scaffolds are popular materials in all areas of tissue engineering because they mimic the fibrous component of the natural extracellular matrix In this chapter we focused on the application of nanofibers in skin tissue engineering and wound healing because the skin is an organ with several vitally important functions particularly barrier thermoregulatory and sensory functions
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